
Sugestão de leitura
TNFα-Induced Oxidative Stress and Mitochondrial Dysfunction Alter Hypothalamic Neurogenesis and Promote Appetite Versus Satiety Neuropeptide Expression in Mice.
Mina Desai, Linsey Stiles, Adriana Torsoni, Marcio Torsoni, Orian Shirihai and Michael Ross
Innovation and dissemination actions
Education workshops
In partnership with theFAPESP Research Center for Obesity and Comorbidities We hold, every six months, education and scientific dissemination workshops with students from public schools in the Limeira-SP region.
* photographic records prior to the COVID-19 pandemic
Webinars
In partnership with theDevelopmental Origins of Health and Disease, DOHaD Brazil, we hold a series of lectures on the MPPM theme every fortnight, on Thursdays at 4pm.
The lectures are also deposited in theDOHaD Brasil channel on Youtube!
Diffusion course
In partnership with the Dean of Extension and Culture, the Unicamp Extension School and the Faculty of Applied Sciences, we held, from 30/05 to 04/06, the first course on METHODOLOGIES IN NEUROSCIENCE: IMMUNOFLUORESCENCE.
This course covered the discussion of practical protocols and “troubleshooting” on the collection and processing of brain tissue and analogues for immunofluorescence analysis on tissue slides.
Information: https://www.extecamp.unicamp.br/dados.asp?sigla=%81a%D8%C2%5E%E3%DE%98&of=%F7%12%A8
Participation in events

From August 6th to 9th, 2022, members of the MPPC Center participated in the FESBE Annual Meeting in its XXXVI edition together with the LVII Annual Meeting of the Brazilian Society of Physiology (SBFis - Founding Society of FESBE) and the1st Annual Meeting of the recently created DOHaD Society (Developmental Origins of Health and Disease), the most recently affiliated with FESBE.
The event took place online and featured lectures by professors Michael Ross, Mina Desai, Kelly Coca and Bernardo Horta.
More information: https://app.virtualieventos.com.br/fesbe2022/info
Participation in events
Between August 27th and 31st, 2022, the “DOHaD World Congress 2022” and the MPPM Center was present!
An event that attempts to address the breadth of the DOHaD concept from basic science and clinical research to social and political sciences.
The group presented at least 8 scientific works at the meeting and received two awards:
-KBHN LMIC Travel Awards for the oral presentation of the work "EPigenetic modulation of hypothalamic cholinergic anti-inflammatory response in mice fetuses of obese pregnancies" main authored by Postdoctoral Researcher, Lais Simino.
-DOHAD 2022 Poster Awards by the poster "Maternal normolipidic interesterified palm oil diet consumption could negatively modulate insulin signaling in young offspring", mainly authored by Undergraduate Paloma Villalta
Furthermore, the event was an opportunity for the First In-Person Meeting of the MPPM Center Project, where teachers were presentmichael ross It isMina Desai from UCLA,Adriana It isMárcio Torsoni from UNICAMP andKelly Coca from Unifesp.

Participation in events
Between the 27th and 30th of August 2023, theXXXVII Annual Meeting of FeSBE and the II DOHaD Brazil Congress with mass participation from@labdime.unicamp .
The group presented at least 5 scientific works on the Dohad theme and 7 more on metabolic disorders and received four awards:
-Honorable mention Fesbe 2023 for presenting the work: MATERNAL INTAKE OF A HIGH-FAT DIET DURING PREGNANCY AND LACTATION HAS THE POTENTIAL TO CAUSE MORE PRONOUNCED CHANGES IN OFFSPRING’S PHENOTYPE AND MILK INTAKE, WHEN COMPARED TO A CONTROL MATERNAL DIET. Baqueiro MN, Silva MJ, Simino LAP, Costa JP, Panzarin C, Torsoni MA, IgnácioSouza L, Coca KP, Ross MG, Desai M, Torsoni AS
- Honorable Mention DOHaD Brazil – Prof. Marco Antonio Barbieri for the oral presentation of the work "SEX-SPECIFICS DIFFERENCES IN INDICATORS OF GUT PERMEABILITY AND MICROBIOME COMPOSITION IN OFFSPRING OF MOTHERS FED A HIGH-FAT DIET" Costa, JP, Nascimento LCP, Baqueiro MN, Costa LC, Silva FA, Chaves WF, Costa SO, Torsoni MA, Torsoni AS.
Furthermore, the event was an opportunity for the Dohad Brasil assembly and professors Márcio and Adriana Torsoni were elected to the composition of the Association's Deliberative and Fiscal Council for the 2023-2025 term..

